Since 1959, the Department of Radiation Oncology began radiation treatment by using 250KV X-ray and 100KV X-ray equipment, and, in 1962, brought in Radium-226 for the first time outside the northern district of Han River in South Korea. And, it performed Korea’s first intracavitary radiation for uterine cancer and provided superficial and gynecologic cancer treatment. From 1971, it treated patients by using Philips Cobalt-60, and, from 1985, was promoted as an independent department. As a result, the department built a new building in which state-of-art equipment including high energy linear accelerator, radiation simulation device, radiation treatment planning device, and various radiation measuring equipment, and ran a cancer center based on modern radiation treatment. Since 1992, the department has developed and provided cranial stereotactic radiosurgery, and, in 2008, began to perform radiosurgery by using the Brain Lab equipment. Since then, following rapid development of computer and radiation technology and equipment, it brought in 3D radiation treatment, tomotherapy, RGRT, and total body radiosurgery systems in order to provide more comfortable environment and up-to-date cancer treatment. On September 27, 2010, the cancer center was expanded and moved and the Hematopoietic Stem Cell Transplantation Center and Weizmann Korea Cancer Vaccine Lab were opened, as part of the department’s effort to provide more systematic, multi-disciplinary treatment for cancer patients. In addition, in December 2010, DSMC introduced the state-of-art radiation treatment device RapidArc for the first time in Daegu. Intracavitary radiation, which had been used since 1962 for uterine cancer patients, was replaced in July 2015 by MRI-based 3D proximity radiation equipment.